CapM (Cap Analog) (100mM) _10682ES

YeasenSKU: 10682ES10

Size: 10 μL
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Description

CapM is a cap analogue with the structure of m7G(UNA)(5′)ppp(5′)(2’OMeA)pG, the molecular formula of it is C32H45N15O24P4 and the molecular weight is 1147.69. The product is used for transcription with the initial sequence of 5'AG3', and the natural cap1 structure is produced by Cap1 transcription capping. Compared with Cap0 produced by traditional capping method, the cap1 structure produced by CapM enables the mRNA to have higher activity and translation efficiency in vivo.

Components

Components No.

Name

Cat. No.

Size

10682

CapM (Cap Analog)  (100mM) 

10682ES10

10 μL

10682ES60

100 μL

10682ES80

1 mL


Product Details

Molecular Formula

 C32H45N15O24P4 (Ammonium Solution)

Molecular weight

1147.69 

Concentration

100± 3 mM

Purity

>98%

Data

Cap analogs mRNA Yield (μg) mRNA integrity Capping Rate
Cap AG 182 90.50% 99.00%
CapM 188 91.20% 99.10%


Table 1. The CapM has similar mRNA yields, integrity and capping rate compared to that of Cap AG.


Figure 1.Luciferase mRNA capped with CapM exhibits prolonged expression.

Storage

This product could be stored at -25~-15 ℃ for two years.

Precautions

  1. For your safety and health, please wear personal protective equipment (PPE), such as laboratory coats and disposable gloves, when operating with this product.
  2. For research use only.

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